SCHEMBL30997398

SCHEMBL30997398

C[C@H](F)[C@H](N)Cc1cc2c(NCc3ccncn3)nc(Cl)nn2c1Br

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.32
RXRA P19793 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
PDE1A P54750 1/20 0.31
PDE1B Q01064 1/20 0.31
PDE1C Q14123 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30997368 0.84 KCNH3 (0.34) KCNH3
SCHEMBL30948894 0.81 RXFP1 (0.37)
SCHEMBL30997387 0.81 DYRK3 (0.34)
SCHEMBL31010618 0.81 TLR7 (0.30)
SCHEMBL30997365 0.81 PDE2A (0.33)
SCHEMBL30948888 0.81 TP53 (0.36)
SCHEMBL31030155 0.79 KCNN1 (0.38)
SCHEMBL31030134 0.79
SCHEMBL31030122 0.79
SCHEMBL31030126 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651950-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2024155842-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed