SCHEMBL30997486

SCHEMBL30997486

N#Cc1cc(CBr)ccc1Oc1ccc(C(F)(F)F)cn1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
HPGD P15428 1/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.45
THRB P10828 1/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 2/20 0.41
LIPE Q05469 2/20 0.40
SCN9A Q15858 3/20 0.40
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29265119 1.00 L3MBTL1 (0.50) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL875974 0.88 L3MBTL1 (0.50) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL30997487 0.88 L3MBTL1 (0.50) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL9101655 0.88 L3MBTL1 (0.50) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL876438 0.86 L3MBTL1 (0.46) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL9105550 0.86 L3MBTL1 (0.46) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL9106108 0.81 L3MBTL1 (0.50) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL3458686 0.81 SMN1; SMN2 (0.55) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL875862 0.79 L3MBTL1 (0.47) L3MBTL1HPGDMAPTKMT2ATHRB
SCHEMBL875636 0.79 L3MBTL1 (0.49) L3MBTL1HPGDMAPTKMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748841-A1 BICYCLO[5,6] IMIDAZOLE PYRIMIDONE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF Shujing Biopharma Co., Ltd (CN) 2026-05-27 EP disclosed
WO-2025015951-A1 BICYCLO[5,6] IMIDAZOLE PYRIMIDONE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海枢境生物科技有限公司 2025-01-23 WO disclosed
CN-119320393-A Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof 上海枢境生物科技有限公司 2025-01-17 CN disclosed
CN-118221687-B Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof 上海枢境生物科技有限公司 2024-12-31 CN disclosed
CN-118221687-A Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof 上海枢境生物科技有限公司 2024-06-21 CN disclosed