SCHEMBL30997487

SCHEMBL30997487

N#Cc1cc(CO)ccc1Oc1ccc(C(F)(F)F)cn1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
AR P10275 2/20 0.47
HPGD P15428 1/20 0.46
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.43
LIPE Q05469 2/20 0.43
SCN9A Q15858 2/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.40
S1PR1 P21453 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875974 1.00 L3MBTL1 (0.50) L3MBTL1ARHPGDKMT2AMAPT
SCHEMBL876438 0.91 L3MBTL1 (0.46) L3MBTL1ARHPGDKMT2AMAPT
SCHEMBL30997486 0.88 L3MBTL1 (0.50) L3MBTL1HPGDKMT2AMAPTLIPE
SCHEMBL9101655 0.88 L3MBTL1 (0.50) L3MBTL1HPGDKMT2AMAPTLIPE
SCHEMBL29265119 0.88 L3MBTL1 (0.50) L3MBTL1HPGDKMT2AMAPTLIPE
SCHEMBL9105550 0.86 L3MBTL1 (0.46) L3MBTL1HPGDKMT2AMAPTLIPE
SCHEMBL875200 0.83 L3MBTL1 (0.54) L3MBTL1HPGDKMT2AMAPTLIPE
SCHEMBL9106108 0.81 L3MBTL1 (0.50) L3MBTL1HPGDKMT2AMAPTSCN9A
SCHEMBL875188 0.81 XDH (0.42) L3MBTL1ARSCN9AS1PR1MRGPRX4
SCHEMBL9889489 0.81 XDH (0.42) ARSCN9AS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119320393-A Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof 上海枢境生物科技有限公司 2025-01-17 CN disclosed
CN-118221687-B Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof 上海枢境生物科技有限公司 2024-12-31 CN disclosed
CN-118221687-A Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof 上海枢境生物科技有限公司 2024-06-21 CN disclosed