Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 5/20 | 0.33 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937375 | 0.73 | BACE1 (0.44) | BACE1TYMSABL1BCHEACHE | |
| SCHEMBL17844908 | 0.73 | BACE1 (0.44) | BACE1TYMSABL1BCHEACHE | |
| SCHEMBL22063607 | 0.69 | BACE1 (0.41) | BACE1TYMSABL1BCHEACHE | |
| SCHEMBL22063697 | 0.69 | REN (0.43) | BACE1TYMSABL1ALDH1A1MPO | |
| SCHEMBL27051371 | 0.69 | BACE1 (0.41) | BACE1TYMSABL1BCHEACHE | |
| SCHEMBL31610283 | 0.67 | ALDH1A1 (0.41) | BACE1TYMSACHEALDH1A1CYP1A2 | |
| SCHEMBL936886 | 0.64 | CYP1B1 (0.40) | TYMSALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL29937127 | 0.63 | PDPK1 (0.38) | ABL1 | |
| SCHEMBL11813362 | 0.63 | CYP1A2 (0.40) | BACE1TYMSCYP1A2CYP2A6SLC6A2 | |
| SCHEMBL30377849 | 0.62 | CYP1A2 (0.52) | BACE1TYMSALDH1A1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | BACE1 3495/4885TYMS 3045/4885ABL1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.