SCHEMBL125043

SCHEMBL125043

CO[Si](CCCN1CCOCC1)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
KEAP1 Q14145 1/20 0.48
TSHR P16473 2/20 0.46
CYP2D6 P10635 2/20 0.46
HPGD P15428 1/20 0.44
DUSP3 P51452 1/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
HTR2A P28223 1/20 0.44
SCN1A P35498 1/20 0.44
HTR2B P41595 1/20 0.44
KCNH2 Q12809 1/20 0.44
SCN2A Q99250 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
SCN3A Q9NY46 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31687713 0.91 SMN1; SMN2 (0.44) SMN1; SMN2KEAP1TSHRCYP2D6HPGD
SCHEMBL31687755 0.91 SMN1; SMN2 (0.44) SMN1; SMN2KEAP1TSHRCYP2D6HPGD
SCHEMBL12802541 0.88 TDP1 (0.44) SMN1; SMN2KEAP1TSHRCYP2D6HPGD
SCHEMBL11897301 0.86 MAPT (0.37) KCNH2SIGMAR1LMNA
SCHEMBL4361438 0.86 MAPT (0.37) KCNH2SIGMAR1LMNA
SCHEMBL612240 0.85 SMN1; SMN2 (0.48) SMN1; SMN2KEAP1TSHRCYP2D6HPGD
SCHEMBL3482540 0.85 SMN1; SMN2 (0.48) SMN1; SMN2KEAP1TSHRCYP2D6HPGD
SCHEMBL30998792 0.83 TDP1 (0.46) TSHRCYP2D6HPGDDUSP3ALDH1A1
SCHEMBL329772 0.82 HRH3 (0.46) CYP2D6ALDH1A1CYP1A2KCNH2SIGMAR1
SCHEMBL31687711 0.81 SMN1; SMN2 (0.46) SMN1; SMN2KEAP1TSHRCYP2D6HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574305-A Preparation method of styrene-butadiene rubber for semisteel tread 万华化学集团股份有限公司 2026-02-27 CN claimed
CN-119264685-A Asphalt special for airport pavement and preparation method thereof 山东海韵沥青有限公司 2025-01-07 CN claimed
US-20150056383-A1 High Resolution Printing INTRINSIQ MATERIALS LTD. (GB) 2015-02-26 US claimed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP claimed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US claimed
EP-0147703-B1 IMPROVED ELECTROEROSION RECORDING MATERIAL WITH A PROTECTIVE LUBRICANT OVERLAYER International Business Machines Corporation (US) 1988-11-23 EP claimed
EP-0147703-A2 Improved electroerosion recording material with a protective lubricant overlayer International Business Machines Corporation (US) 1985-07-10 EP claimed
JP-58122517-A None JP disclosed
EP-3858877-B1 POLYFUNCTIONAL VINYL AROMATIC COPOLYMER AND METHOD FOR MANUFACTURING SAME, COPOLYMER RUBBER OBTAINED THEREFROM, RUBBER COMPOSITION, RUBBER CROSSLINKED MATERIAL, AND TIRE MEMBER NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2026-05-27 EP disclosed
US-12606576-B2 Method for producing nitrogen-containing organoxysilane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-21 US disclosed
US-20260071058-A1 MASTERBATCH FOR RUBBER MODIFICATION AND BRANCHED CONJUGATED DIENE POLYMER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-12 US disclosed
EP-4703397-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-04 EP disclosed
EP-4703396-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER Asahi Kasei Kabushiki Kaisha (JP) 2026-03-04 EP disclosed
US-4596733-A Nonconductive support, thin layer of conductive material, protective lubricant comprising dispersed particles in polysiloxane binder INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1986-06-24 US disclosed
EP-0184966-A1 Silicone composition vulcanizable at ambient temperature into an adherent elastomer RHONE-POULENC CHIMIE (FR) 1986-06-18 EP disclosed
EP-0154980-A1 Negative working light-sensitive lithographic plate requiring no dampening solution and plate making process FUJI PHOTO FILM CO., LTD. (JP) 1985-09-18 EP disclosed
EP-0147703-A2 Improved electroerosion recording material with a protective lubricant overlayer International Business Machines Corporation (US) 1985-07-10 EP disclosed
US-4496647-A Treatment of image-forming laminated plate TORAY INDUSTRIES, INC. (JP) 1985-01-29 US disclosed
EP-0100938-A2 Treatment of image-forming laminated plate TORAY INDUSTRIES, INC. (JP) 1984-02-22 EP disclosed
JP-S58122517-A ORIENTATION TREATMENT OF LIQUID CRYSTAL CELL SHARP CORP 1983-07-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071058-A1 MASTERBATCH FOR RUBBER MODIFICATION AND BRANCHED CONJUGATED DIENE POLYMER COMPOSITION COL1A1, TGFBR1, COL2A1 SMN1; SMN2 154/4885KEAP1 758/4885TSHR 4527/4885
US-12606576-B2 Method for producing nitrogen-containing organoxysilane compound HRH3, HRH4, H1-0 SMN1; SMN2 1338/4885KEAP1 1193/4885TSHR 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.