Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.60 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.51 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL20266257 | 1.00 | FBP1 (0.60) | FBP1HSPA5NT5ESIRT2SIRT1 | |
| SCHEMBL8388000 | 0.92 | FBP1 (0.64) | FBP1SIRT2SIRT1ENTPD1 | |
| SCHEMBL20266254 | 0.91 | FBP1 (0.63) | FBP1SIRT2SIRT1ENTPD1 | |
| SCHEMBL4209829 | 0.88 | ENTPD1 (0.66) | FBP1NT5EENTPD1 | |
| SCHEMBL11405944 | 0.87 | HSPA5 (0.64) | FBP1HSPA5HSPA8RXFP1 | |
| SCHEMBL4206199 | 0.87 | ENTPD1 (0.67) | FBP1NT5EENTPD1 | |
| Adenosine Phosphate SCHEMBL31666008 | 0.86 | P2RY1 (0.69) | FBP1NT5E | |
| SCHEMBL20529826 | 0.86 | P2RY1 (0.65) | FBP1NT5E | |
| SCHEMBL10686147 | 0.85 | FBP1 (0.68) | FBP1SIRT2SIRT1ENTPD1 | |
| SCHEMBL5924577 | 0.84 | FBP1 (0.72) | FBP1HSPA5HSPA8RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4403042-A2 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | Mars, Incorporated (US) | 2024-07-24 | — | — | EP | disclosed |