Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 16/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000100 | 0.95 | IGF1R (0.39) | IGF1RKCNH2ALKCDK4CCND1 | |
| SCHEMBL31000072 | 0.92 | CDK4 (0.45) | IGF1RALKCDK4CCND1CCND3 | |
| SCHEMBL31000311 | 0.87 | CDK4 (0.45) | IGF1RALKCDK4CCND1CCND3 | |
| SCHEMBL31000233 | 0.87 | CDK4 (0.45) | IGF1RALKCDK4CCND1CCND3 | |
| SCHEMBL31000209 | 0.87 | CDK4 (0.43) | IGF1RALKCDK4CCND1CCND3 | |
| SCHEMBL31000174 | 0.86 | CDK4 (0.44) | IGF1RALKCDK4CCND1CCND3 | |
| SCHEMBL31000195 | 0.82 | CFTR (0.36) | IGF1RCDK4CCND1CCND3CDK6 | |
| SCHEMBL31000133 | 0.81 | CDK7 (0.42) | IGF1RKCNH2CDK2INSR | |
| SCHEMBL31000196 | 0.81 | CFTR (0.39) | IGF1RALKCDK4CCND1CCND3 | |
| SCHEMBL31000294 | 0.81 | CDK7 (0.50) | IGF1RKCNH2CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |