Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.42 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22228831 | 0.89 | CCNT1 (0.54) | CDK2MAPK8MAPK9JUNDYRK2 | |
| SCHEMBL20455517 | 0.87 | CDK2 (0.46) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL31500996 | 0.87 | CDK2 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL20455526 | 0.87 | CDK2 (0.58) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL20460636 | 0.83 | FLT3 (0.46) | CDK2MAPK8MAPK9JUNIGF1R | |
| SCHEMBL31501006 | 0.82 | CCNT1 (0.54) | DYRK2CCNT1FLT3CDK9 | |
| SCHEMBL22228724 | 0.82 | CCNT1 (0.54) | DYRK2CCNT1FLT3CDK9 | |
| SCHEMBL31000156 | 0.79 | CDK4 (0.45) | CDK2DYRK2IGF1RCDK4CCND1 | |
| SCHEMBL22228776 | 0.79 | CDK9 (0.59) | CDK2MAPK8MAPK9CCNT1FLT3 | |
| SCHEMBL31000140 | 0.78 | CDK4 (0.44) | CDK2DYRK2IGF1RCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3577116-B1 | DERIVATIVES OF N-CYCLOALKYL/HETEROCYCLOALKYL-4-(IMIDAZO[1,2-A]PYRIDINE)PYRIMIDIN-2-AMINE AS THERAPEUTIC AGENTS | CHANGZHOU QIANHONG BIO PHARMA CO LTD (CN) | 2025-04-23 | — | — | EP | disclosed |