Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542494 | 0.90 | CHRM5 (0.40) | CHRM5 | |
| SCHEMBL31000158 | 0.80 | CHRM5 (0.37) | CHRM5 | |
| SCHEMBL31000193 | 0.78 | CHRM5 (0.34) | CHRM5 | |
| SCHEMBL31739627 | 0.77 | CHRM5 (0.33) | CHRM5 | |
| SCHEMBL31000167 | 0.76 | CHRM5 (0.33) | CHRM5 | |
| SCHEMBL31000098 | 0.76 | CNR2 (0.35) | CHRM5 | |
| SCHEMBL31739938 | 0.74 | CHRM5 (0.35) | CHRM5 | |
| SCHEMBL31000181 | 0.74 | ADRA1A (0.33) | CHRM5 | |
| SCHEMBL31000094 | 0.73 | CHRM5 (0.40) | CHRM5 | |
| SCHEMBL31000264 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |