⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639411 | 0.78 | NRAS (0.31) | — | |
| SCHEMBL24975689 | 0.75 | PDE10A (0.36) | — | |
| SCHEMBL31000221 | 0.74 | DYRK1A (0.38) | — | |
| SCHEMBL24975688 | 0.74 | PDE10A (0.34) | — | |
| SCHEMBL31000205 | 0.73 | CHRM5 (0.38) | — | |
| SCHEMBL31739611 | 0.70 | DYRK1A (0.37) | — | |
| SCHEMBL29682761 | 0.69 | FLT3 (0.42) | — | |
| SCHEMBL24542495 | 0.69 | FLT3 (0.42) | — | |
| SCHEMBL31000261 | 0.69 | IGF1R (0.38) | — | |
| SCHEMBL31000231 | 0.69 | NRAS (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |