Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRAS | P01111 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 12/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000211 | 0.91 | IGF1R (0.32) | NRASFLT3FYNIGF1RCDK2 | |
| SCHEMBL31000128 | 0.90 | IGF1R (0.32) | NRASFLT3FYNIGF1RCDK2 | |
| SCHEMBL31639175 | 0.87 | NRAS (0.36) | NRASFLT3FYNIGF1RCDK2 | |
| SCHEMBL31000261 | 0.87 | IGF1R (0.38) | IGF1RCDK2 | |
| SCHEMBL27332713 | 0.83 | NRAS (0.36) | NRASFLT3FYNTRPC6 | |
| SCHEMBL31000279 | 0.82 | FYN (0.35) | FYNIGF1RCDK2PIK3CAMTOR | |
| SCHEMBL31639411 | 0.81 | NRAS (0.31) | NRASFLT3FYN | |
| SCHEMBL31000256 | 0.80 | FYN (0.34) | FYNIGF1RCDK2PIK3CAMTOR | |
| SCHEMBL27327582 | 0.79 | NRAS (0.35) | NRASFLT3FYNPIK3CAMTOR | |
| SCHEMBL31639512 | 0.79 | PDE4D (0.33) | NRASFLT3FYNPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |