Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.31 |
| ▸ | NRAS | P01111 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000231 | 0.90 | NRAS (0.34) | IGF1RCDK2FYNNRASFLT3 | |
| SCHEMBL31000211 | 0.87 | IGF1R (0.32) | IGF1RCDK2FYNNRASFLT3 | |
| SCHEMBL30698348 | 0.80 | PIK3CA (0.33) | FYNNRASFLT3PIK3CAMTOR | |
| SCHEMBL31000236 | 0.79 | FYN (0.32) | FYN | |
| SCHEMBL31000279 | 0.79 | FYN (0.35) | IGF1RCDK2FYNPIK3CAMTOR | |
| SCHEMBL31000261 | 0.78 | IGF1R (0.38) | IGF1RCDK2 | |
| SCHEMBL31639175 | 0.78 | NRAS (0.36) | IGF1RCDK2FYNNRASFLT3 | |
| SCHEMBL31000244 | 0.78 | TRPC6 (0.31) | — | |
| SCHEMBL31000256 | 0.76 | FYN (0.34) | IGF1RCDK2FYNPIK3CAMTOR | |
| SCHEMBL31000302 | 0.76 | FYN (0.33) | FYNNRASFLT3PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |