Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000138 | 0.87 | PDE4D (0.37) | CFTRPDE4DHPGDKDM4EMEN1 | |
| SCHEMBL31000243 | 0.86 | CFTR (0.39) | USP30CFTRPDE4BCDK2CCNT1 | |
| SCHEMBL31000195 | 0.86 | CFTR (0.36) | USP30CFTRPDE4DHPGDKDM4E | |
| SCHEMBL31000196 | 0.82 | CFTR (0.39) | CFTRPDE4BHPGDKDM4EMEN1 | |
| SCHEMBL31000124 | 0.81 | PDE4B (0.36) | CFTRPDE4BHPGDKDM4EMEN1 | |
| SCHEMBL24542620 | 0.81 | FLT3 (0.40) | USP30CFTRHPGDKDM4EMEN1 | |
| SCHEMBL31000106 | 0.80 | CFTR (0.37) | USP30CFTRPDE4BEIF2AK4CDK2 | |
| SCHEMBL31000194 | 0.80 | CFTR (0.38) | USP30CFTREIF2AK4CCNT1CDK9 | |
| SCHEMBL31000214 | 0.80 | MAPK8 (0.36) | CDK2MAPK9JUNMAPK8MAPK10 | |
| SCHEMBL31000115 | 0.80 | CFTR (0.40) | CFTRPDE4BPDE4DCDK2MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |