Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31001611 | 0.97 | DOT1L (0.48) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001625 | 0.93 | DOT1L (0.48) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001581 | 0.92 | DOT1L (0.48) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001586 | 0.92 | DOT1L (0.48) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001549 | 0.92 | DOT1L (0.47) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001587 | 0.91 | DOT1L (0.50) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001541 | 0.90 | DOT1L (0.49) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001565 | 0.89 | P2RX3 (0.49) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001519 | 0.82 | DOT1L (0.57) | DOT1LP2RX3P2RX1P2RX4P2RY12 | |
| SCHEMBL31001622 | 0.82 | P2RX3 (0.52) | DOT1LP2RX3P2RX1P2RX4P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177959-A1 | SMALL MOLECULE TRACER LIGANDS FOR AMINOACYL-TRNA SYNTHETASE ASSAYS | THE GENERAL HOSPITAL CORPORATION (US) | 2024-08-29 | — | — | WO | disclosed |