Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539315 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL11804424 | 0.86 | HTT (0.62) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL15666735 | 0.85 | HTT (0.57) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL1986986 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL634335 | 0.84 | HTT (0.65) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL14700589 | 0.84 | NPC1 (0.54) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL13094612 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL1179412 | 0.82 | HTT (0.58) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL17420537 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL5944070 | 0.82 | HTT (0.58) | ALDH1A1HPGDCYP3A4MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160276-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | disclosed |