Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181669 | 0.90 | CA1 (0.55) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL146258 | 0.85 | KDM4E (0.62) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29502160 | 0.85 | KDM4E (0.62) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5944070 | 0.85 | HTT (0.58) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL382822 | 0.84 | KDM4E (0.66) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11804424 | 0.84 | HTT (0.62) | HTTKDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23540433 | 0.84 | KDM4E (0.51) | HTTKDM4ECA1CA2NPC1 | |
| SCHEMBL516908 | 0.84 | KDM4E (0.45) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL28744755 | 0.84 | KDM4E (0.49) | HTTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3481769 | 0.84 | HPGD (0.58) | HTTKDM4ECA1CA2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310094-A1 | METHOD FOR PRODUCING AMINO ACID OR PEPTIDE, REAGENT FOR FORMING PROTECTING GROUP, AND COMPOUND | FUJIFILM Corporation (JP) | 2024-01-24 | — | — | EP | disclosed |
| US-20240002432-A1 | METHOD FOR PRODUCING AMINO ACID OR PEPTIDE, PROTECTIVE GROUP-FORMING REAGENT, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2024-01-04 | — | — | US | disclosed |
| US-11858889-B2 | Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858889-B2 | Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| CN-116997559-A | Method for producing amino acid or peptide, reagent for forming protecting group, and compound | 富士胶片株式会社 | 2023-11-03 | — | — | CN | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20220339302-A1 | ISOINDOLINONE COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2022-10-27 | — | — | US | disclosed |
| US-10927104-B2 | Ether compounds and uses thereof | BIOTHERYX, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. | 2020-07-23 | — | — | US | disclosed |
| EP-3672955-A1 | ETHER COMPOUNDS AND USES THEREOF | Biotheryx Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| US-6846832-B2 | 2,3-dihydro-isoindol-1-one derivatives | HOFFMAN-LA ROCHE INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040082603-A1 | 2,3-Dihydro-isoindol-1-one derivatives | HOFFMANN-LA ROCHE INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004014856-A1 | 2,3-DIHYDRO-ISOINDOL-1-ONES WITH MAO-B INHIBITING ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014856-A1 | 2,3-DIHYDRO-ISOINDOL-1-ONES WITH MAO-B INHIBITING ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-19 | — | — | WO | disclosed |
| US-20030212094-A1 | Novel cyclic amide derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1260512-A1 | NOVEL CYCLIC AMIDE DERIVATIVES | Mitsubishi Pharma Corporation (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |
| US-4444567-A | ALKOXY BENZALDEHYDES, ALKOXY BENZOATES | PHILLIPS PETROLEUM COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | EPCAM, ICAM1, SELE | HTT 1328/4885KDM4E 1455/4885CYP1A2 3444/4885 |
| US-20240002432-A1 | METHOD FOR PRODUCING AMINO ACID OR PEPTIDE, PROTECTIVE GROUP-FORMING REAGENT, AND COMPOUND | NGLY1, VIP, FPR1 | HTT 951/4885KDM4E 4661/4885CYP1A2 3708/4885 |
| US-20220339302-A1 | ISOINDOLINONE COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | HTT 1/4885KDM4E 4701/4885CYP1A2 4845/4885 |
| US-20040082603-A1 | 2,3-Dihydro-isoindol-1-one derivatives | MAOB, MAOA, COMT | HTT 602/4885KDM4E 2782/4885CYP1A2 4/4885 |
| US-20030212094-A1 | Novel cyclic amide derivatives | SIGMAR1, OPRM1, OPRD1 | HTT 4761/4885KDM4E 2058/4885CYP1A2 271/4885 |
| US-11858889-B2 | Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease | ADM2, DDAH1, BHMT | HTT 788/4885KDM4E 3545/4885CYP1A2 1125/4885 |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | HTT 3790/4885KDM4E 1763/4885CYP1A2 4095/4885 |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | EPCAM, ICAM1, SELE | HTT 1328/4885KDM4E 1455/4885CYP1A2 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.