Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.52 |
| ▸ | PLG | P00747 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31004014 | 0.94 | TDP1 (0.63) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL31004030 | 0.91 | FOLH1 (0.57) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL31004025 | 0.85 | FOLH1 (0.54) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL31003997 | 0.85 | TDP1 (0.58) | FOLH1TDP1CAPN1 | |
| SCHEMBL29439904 | 0.84 | TDP1 (0.75) | FOLH1TDP1CAPN1PKM | |
| SCHEMBL31003985 | 0.84 | FOLH1 (0.48) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL24858374 | 0.83 | TDP1 (0.73) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL29439931 | 0.83 | TDP1 (0.73) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL29340332 | 0.83 | FOLH1 (0.59) | FOLH1TDP1PRSS1PRSS2PRSS3 | |
| SCHEMBL31003984 | 0.82 | FOLH1 (0.51) | FOLH1TDP1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151843-A1 | TARGETED UNIVERSAL DELIVERY SYSTEM OF DON AND OTHER DRUGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |