Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31004002 | 0.94 | FOLH1 (0.61) | TDP1CAPN1FOLH1PLGPRSS1 | |
| SCHEMBL29439904 | 0.90 | TDP1 (0.75) | TDP1CAPN1FOLH1CA12CA1 | |
| SCHEMBL31003997 | 0.90 | TDP1 (0.58) | TDP1CAPN1FOLH1CA12CA1 | |
| SCHEMBL24858374 | 0.88 | TDP1 (0.73) | TDP1CAPN1FOLH1CA12CA1 | |
| SCHEMBL29439931 | 0.88 | TDP1 (0.73) | TDP1CAPN1FOLH1CA12CA1 | |
| SCHEMBL31004030 | 0.85 | FOLH1 (0.57) | TDP1CAPN1FOLH1CNR1PLG | |
| SCHEMBL31004020 | 0.83 | CASP3 (0.53) | TDP1CAPN1FOLH1CA12CA1 | |
| SCHEMBL31004015 | 0.83 | TDP1 (0.51) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL20417372 | 0.82 | TDP1 (0.85) | TDP1CAPN1FOLH1CA12CA1 | |
| SCHEMBL12372458 | 0.82 | TDP1 (0.85) | TDP1CAPN1FOLH1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151843-A1 | TARGETED UNIVERSAL DELIVERY SYSTEM OF DON AND OTHER DRUGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |