Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31003985 | 0.94 | FOLH1 (0.48) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31003997 | 0.93 | TDP1 (0.58) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31004004 | 0.92 | CASP3 (0.44) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31003983 | 0.90 | CASP3 (0.43) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31004030 | 0.88 | FOLH1 (0.57) | TDP1CAPN1FOLH1CNR1PLG | |
| SCHEMBL31004034 | 0.86 | CASP3 (0.48) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31004023 | 0.85 | FOLH1 (0.47) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31004014 | 0.83 | TDP1 (0.63) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL31003988 | 0.82 | TDP1 (0.49) | TDP1CAPN1FOLH1CNR1 | |
| SCHEMBL29340332 | 0.80 | FOLH1 (0.59) | TDP1CAPN1FOLH1CNR1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151843-A1 | TARGETED UNIVERSAL DELIVERY SYSTEM OF DON AND OTHER DRUGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |