SCHEMBL3100459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1727314	0.93	PTGES (0.57)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL3106270	0.91	PTGES (0.69)	PTGESHDAC6
	SCHEMBL11963647	0.90	PTGES (0.54)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL3106460	0.89	PTGES (0.59)	PTGESHDAC6MEN1KMT2AATM
	SCHEMBL3098320	0.89	PTGES (0.52)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL11894436	0.88	PTGES (0.53)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL3099420	0.88	PTGES (0.53)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL11894503	0.88	PTGES (0.52)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL3106295	0.88	PTGES (0.52)	PTGESNPC1RAB9AHDAC6MEN1
	SCHEMBL3103895	0.87	PTGES (0.52)	PTGESNPC1RAB9AHDAC6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.