Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 4/20 | 0.32 |
| ▸ | LAP3 | P28838 | 3/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100608 | 1.00 | FDPS (0.33) | FDPSANPEPLAP3ERAP1PGD | |
| SCHEMBL3098133 | 0.88 | LAP3 (0.38) | FDPSANPEPLAP3ERAP1GABBR2 | |
| SCHEMBL3098142 | 0.88 | LAP3 (0.38) | FDPSANPEPLAP3ERAP1GABBR2 | |
| SCHEMBL2992439 | 0.82 | FDPS (0.34) | FDPSLAP3 | |
| SCHEMBL2992441 | 0.82 | FDPS (0.34) | FDPSLAP3 | |
| SCHEMBL3087571 | 0.81 | LAP3 (0.36) | FDPSANPEPLAP3ERAP1 | |
| SCHEMBL3087573 | 0.81 | LAP3 (0.36) | FDPSANPEPLAP3ERAP1 | |
| SCHEMBL3109134 | 0.78 | FDPS (0.37) | FDPSANPEPLAP3ERAP1ALDH1A1 | |
| SCHEMBL3109138 | 0.78 | FDPS (0.37) | FDPSANPEPLAP3ERAP1ALDH1A1 | |
| SCHEMBL3095789 | 0.77 | LAP3 (0.35) | ANPEPLAP3ERAP1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |