Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18857950 | 1.00 | ELANE (0.41) | ELANEBRD4CA2CA12CA1 | |
| SCHEMBL18675818 | 0.91 | MTNR1A (0.39) | ELANECA2CA12CA1CA9 | |
| SCHEMBL18089428 | 0.90 | ELANE (0.40) | ELANEBRD4CA2CA12CA1 | |
| SCHEMBL18857968 | 0.88 | KMT2A (0.37) | ELANEBRD4CA9AAK1MEN1 | |
| SCHEMBL18857953 | 0.87 | ELANE (0.40) | ELANECA2CA12CA1CA9 | |
| SCHEMBL31617775 | 0.87 | ELANE (0.40) | ELANECA2CA12CA1CA9 | |
| SCHEMBL25836597 | 0.87 | ELANE (0.40) | ELANEBRD4CA2CA12CA1 | |
| SCHEMBL23414048 | 0.85 | ELANE (0.39) | ELANECA2CA12CA1CA9 | |
| SCHEMBL18857933 | 0.85 | ELANE (0.39) | ELANECA2CA12CA1CA9 | |
| SCHEMBL23413776 | 0.83 | ELANE (0.37) | ELANECA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638140-A | Oxo-substituted compounds | 住友制药株式会社 | 2024-09-13 | — | — | CN | disclosed |
| CN-112135830-B | Oxo-substituted compounds | 住友制药株式会社 | 2024-06-14 | — | — | CN | disclosed |