Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006018 | 0.90 | ELANE (0.41) | ELANECA2MTNR1AMTNR1BBRD4 | |
| SCHEMBL18857950 | 0.90 | ELANE (0.41) | ELANECA2MTNR1AMTNR1BBRD4 | |
| SCHEMBL17410803 | 0.88 | TSHR (0.40) | ELANEAAK1CA9KDM4EHPGD | |
| SCHEMBL18089677 | 0.87 | ELANE (0.35) | ELANECA2AAK1MEN1HTT | |
| SCHEMBL17410802 | 0.85 | ELANE (0.40) | ELANECA2CA12CA1CA7 | |
| SCHEMBL18675818 | 0.81 | MTNR1A (0.39) | ELANECA2MTNR1AMTNR1BCA12 | |
| SCHEMBL18089427 | 0.79 | ELANE (0.37) | ELANECA2BRD4 | |
| SCHEMBL23414048 | 0.78 | ELANE (0.39) | ELANECA2CA12CA1CA9 | |
| SCHEMBL18857968 | 0.78 | KMT2A (0.37) | ELANEBRD4AAK1CA9HSD17B10 | |
| SCHEMBL18857953 | 0.77 | ELANE (0.40) | ELANECA2CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016149393-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2016-09-22 | — | — | WO | disclosed |