Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283829 | 1.00 | HSP90AB1 (0.46) | HSP90AB1RXFP1POLBDHPSROCK2 | |
| SCHEMBL31006511 | 0.89 | HSP90AB1 (0.60) | HSP90AB1TRPA1BACE1TRPM8ACHE | |
| SCHEMBL29283801 | 0.89 | HSP90AB1 (0.60) | HSP90AB1TRPA1BACE1TRPM8ACHE | |
| SCHEMBL29283824 | 0.85 | THRB (0.40) | HSP90AB1POLBTRPA1BACE1TRPM8 | |
| SCHEMBL31006521 | 0.85 | THRB (0.40) | HSP90AB1POLBTRPA1BACE1TRPM8 | |
| SCHEMBL31006510 | 0.84 | HSP90AB1 (0.48) | HSP90AB1DHPSROCK2ROCK1LMNA | |
| SCHEMBL29283815 | 0.84 | HSP90AB1 (0.48) | HSP90AB1DHPSROCK2ROCK1LMNA | |
| SCHEMBL31006545 | 0.83 | HSP90AB1 (0.50) | HSP90AB1RXFP1ROCK2ROCK1MAPT | |
| SCHEMBL29283808 | 0.83 | HSP90AB1 (0.50) | HSP90AB1RXFP1ROCK2ROCK1MAPT | |
| SCHEMBL31006533 | 0.82 | HSP90AB1 (0.48) | HSP90AB1POLBDHPSROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |