Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283800 | 1.00 | ESR1 (0.43) | ESR1ESR2THRBGRM2NLRP3 | |
| SCHEMBL31006540 | 0.91 | THRB (0.43) | ESR1ESR2THRBGRM2HSD17B1 | |
| SCHEMBL29283814 | 0.91 | THRB (0.43) | ESR1ESR2THRBGRM2HSD17B1 | |
| SCHEMBL31006542 | 0.89 | HSP90AB1 (0.46) | THRBGRM2LMNAMKNK1MKNK2 | |
| SCHEMBL29283860 | 0.89 | HSP90AB1 (0.46) | THRBGRM2LMNAMKNK1MKNK2 | |
| SCHEMBL29283798 | 0.88 | THRB (0.43) | THRBGRM2LMNAMKNK1MKNK2 | |
| SCHEMBL29283809 | 0.86 | THRB (0.45) | THRBGRM2LMNAMKNK1MKNK2 | |
| SCHEMBL29283826 | 0.84 | HSP90AB1 (0.41) | THRBGRM2LMNAMKNK1MKNK2 | |
| SCHEMBL31006560 | 0.84 | HSP90AB1 (0.41) | THRBGRM2LMNAMKNK1MKNK2 | |
| SCHEMBL31006562 | 0.84 | THRB (0.42) | ESR2THRBGRM2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |