Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283824 | 1.00 | THRB (0.40) | THRBLMNATP53POLBNR3C1 | |
| SCHEMBL29283849 | 0.89 | THRB (0.45) | THRBLMNATP53POLBALDH1A1 | |
| SCHEMBL29283829 | 0.85 | HSP90AB1 (0.46) | LMNATP53POLBNR3C1TRPA1 | |
| SCHEMBL31006558 | 0.85 | HSP90AB1 (0.46) | LMNATP53POLBNR3C1TRPA1 | |
| SCHEMBL29283803 | 0.84 | THRB (0.42) | THRBLMNATP53POLBALDH1A1 | |
| SCHEMBL31006562 | 0.84 | THRB (0.42) | THRBLMNATP53POLBALDH1A1 | |
| SCHEMBL31006549 | 0.84 | THRB (0.42) | THRBLMNATP53POLBALDH1A1 | |
| SCHEMBL29283818 | 0.84 | THRB (0.42) | THRBLMNATP53POLBALDH1A1 | |
| SCHEMBL31006542 | 0.83 | HSP90AB1 (0.46) | THRBLMNATP53POLBALDH1A1 | |
| SCHEMBL29283860 | 0.83 | HSP90AB1 (0.46) | THRBLMNATP53POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |