Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.64 |
| ▸ | DHPS | P49366 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283822 | 1.00 | GRM2 (0.64) | GRM2DHPSACHEMKNK1MKNK2 | |
| SCHEMBL31006523 | 0.88 | GRM2 (0.47) | GRM2MKNK1MKNK2LMNATP53 | |
| SCHEMBL29283862 | 0.88 | GRM2 (0.47) | GRM2MKNK1MKNK2LMNATP53 | |
| SCHEMBL29283860 | 0.87 | HSP90AB1 (0.46) | GRM2MKNK1MKNK2LMNATP53 | |
| SCHEMBL31006542 | 0.87 | HSP90AB1 (0.46) | GRM2MKNK1MKNK2LMNATP53 | |
| SCHEMBL29283798 | 0.84 | THRB (0.43) | GRM2MKNK1MKNK2LMNATP53 | |
| SCHEMBL31006541 | 0.84 | GRM2 (0.69) | GRM2DHPSCYP11B1CYP11B2CYP17A1 | |
| SCHEMBL29283804 | 0.84 | GRM2 (0.69) | GRM2DHPSCYP11B1CYP11B2CYP17A1 | |
| SCHEMBL29283809 | 0.84 | THRB (0.45) | GRM2MKNK1MKNK2LMNATP53 | |
| SCHEMBL31006519 | 0.82 | ESR1 (0.43) | GRM2MKNK1MKNK2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |