Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283857 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL25419377 | 0.86 | ALDH1A1 (0.43) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL30461664 | 0.86 | ALDH1A1 (0.43) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL29605398 | 0.84 | CA1 (0.50) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL30399721 | 0.80 | HPGD (0.42) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL26176367 | 0.80 | HPGD (0.42) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL12120920 | 0.80 | ABL1 (0.44) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL13302164 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL19250316 | 0.78 | BRD4 (0.54) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL16854194 | 0.78 | ALDH1A1 (0.43) | L3MBTL1ALDH3A1POLBHTTNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | disclosed |