Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | CES2 | O00748 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | RECQL | P46063 | 4/20 | 0.63 |
| ▸ | CES1 | P23141 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 4/20 | 0.63 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.63 |
| ▸ | KDM1A | O60341 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | IDO1 | P14902 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421122 | 0.80 | MEN1 (0.63) | MEN1KMT2AALDH1A1TDP1CES2 | |
| SCHEMBL8199773 | 0.80 | MEN1 (0.63) | MEN1KMT2AALDH1A1TDP1CES2 | |
| SCHEMBL29583434 | 0.79 | MEN1 (0.58) | MEN1KMT2AALDH1A1TDP1CES2 | |
| SCHEMBL16421130 | 0.79 | MEN1 (0.58) | MEN1KMT2AALDH1A1TDP1CES2 | |
| Cryptotanshinone SCHEMBL29387944 | 0.77 | MEN1 (1.00) | MEN1KMT2AALDH1A1TDP1CES2 | |
| Cryptotanshinone SCHEMBL4126834 | 0.77 | MEN1 (1.00) | MEN1KMT2AALDH1A1TDP1CES2 | |
| Cryptotanshinone SCHEMBL5940386 | 0.77 | MEN1 (1.00) | MEN1KMT2AALDH1A1TDP1CES2 | |
| Dihydrotanshinone I SCHEMBL13049977 | 0.72 | TDP1 (1.00) | MEN1KMT2AALDH1A1TDP1CES2 | |
| Dihydrotanshinone I SCHEMBL29351163 | 0.72 | TDP1 (1.00) | MEN1KMT2AALDH1A1TDP1CES2 | |
| Dihydrotanshinone I SCHEMBL29355397 | 0.72 | TDP1 (1.00) | MEN1KMT2AALDH1A1TDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118064391-A | Biological material for regulating and controlling CYP71BE37 gene expression of salvia miltiorrhiza and application thereof | 中国中医科学院中药研究所 | 2024-05-24 | — | — | CN | disclosed |