Dihydrotanshinone I

Dihydrotanshinone I

SCHEMBL29355397

Cc1cccc2c3c(ccc12)C1=C(C(=O)C3=O)[C@@H](C)CO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 1.00
▸ MAPT P10636 5/20 1.00
▸ CES1 P23141 5/20 1.00
▸ MEN1 O00255 4/20 1.00
▸ KMT2A Q03164 4/20 1.00
▸ HIF1A Q16665 4/20 1.00
▸ EPAS1 Q99814 4/20 1.00
▸ KDM4E B2RXH2 4/20 1.00
▸ ACHE P22303 4/20 1.00
▸ ALDH1A1 P00352 3/20 1.00
▸ RECQL P46063 3/20 1.00
▸ CES2 O00748 3/20 1.00
▸ KDM1A O60341 3/20 1.00
▸ PTPN6 P29350 3/20 1.00
▸ PTPN11 Q06124 3/20 1.00
▸ BLM P54132 3/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ THRB P10828 2/20 1.00
▸ IDO1 P14902 2/20 1.00
▸ HPGD P15428 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrotanshinone I SCHEMBL13049977 1.00 TDP1 (1.00) TDP1MAPTCES1MEN1KMT2A
Dihydrotanshinone I SCHEMBL29351163 1.00 TDP1 (1.00) TDP1MAPTCES1MEN1KMT2A
Dihydrotanshinone I SCHEMBL5940466 1.00 TDP1 (1.00) TDP1MAPTCES1MEN1KMT2A
SCHEMBL13568194 0.90 TDP1 (0.81) TDP1MAPTCES1MEN1KMT2A
Dihydroisotanshinone Ii SCHEMBL16421136 0.90 TDP1 (0.81) TDP1MAPTCES1MEN1KMT2A
SCHEMBL24191942 0.90 TDP1 (0.81) TDP1MAPTCES1MEN1KMT2A
SCHEMBL25704340 0.76 MEN1 (0.62) TDP1MAPTCES1MEN1KMT2A
SCHEMBL8199773 0.74 MEN1 (0.63) TDP1MAPTCES1MEN1KMT2A
SCHEMBL16421122 0.74 MEN1 (0.63) TDP1MAPTCES1MEN1KMT2A
SCHEMBL17465219 0.72 MAPT (0.56) TDP1MAPTCES1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059581-A Preparation method of nano filler based on hollow double shells and application of nano filler in preparation of transparent heat-insulating coating 四川轻化工大学 2025-05-30 — — CN claimed
CN-119157886-A Application of dihydrotanshinone I in preparation of medicines for treating cerebral cavernous vascular malformation 南京中医药大学 2024-12-20 — — CN claimed
CN-118883736-A Construction method of double-stone stranguria-treating capsule feature map and feature map thereof 陕西科技大学 2024-11-01 — — CN claimed
CN-114780486-A Distributed storage keyword retrieval method based on IPFS 苏州国本新信息科技有限公司 2022-07-22 — — CN claimed
CN-110720204-B Block chain storage method, storage medium and system based on shared secret 创新先进技术有限公司 2022-06-03 — — CN claimed
US-20260100846-A1 VALIDATING RESULT SETS USING A ZERO TRUST MECHANISM ANYLOG INC (US) 2026-04-09 — — US disclosed
EP-3888334-B1 SYSTEMS AND METHODS FOR DISTRIBUTED RESOURCE ALLOCATION CUTTS SHAUN (US) 2026-04-01 — — EP disclosed
US-20260089092-A1 METHOD AND APPARATUS OF ADDRESS RESOLUTION IN A MANHATTAN GRID NETWORK HUAWEI TECH CO LTD (CN) 2026-03-26 — — US disclosed
US-12585437-B2 System and method for a machine learning source code generation via a holochain network BANK OF AMERICA CORPORATION (US) 2026-03-24 — — US disclosed
US-12575811-B2 Diagnosis of respiratory diseases by capturing aerosolized biomaterial particles using packed bed systems and methods ZETEO TECH, INC. (US) 2026-03-17 — — US disclosed
EP-4184410-B1 OPERATING SYSTEM FOR BLOCKCHAIN IOT DEVICES NCHAIN LICENSING AG (CH) 2026-03-04 — — EP disclosed
EP-4699284-A1 METHOD AND APPARATUS OF ADDRESS RESOLUTION IN MANHATTAN GRID NETWORK Huawei Technologies Co., Ltd. (CN) 2026-02-25 — — EP disclosed
CN-114402647-A Communication server apparatus and method for determining presence of revocation attacks 格步计程车控股私人有限公司 2022-04-26 — — CN disclosed
CN-114375565-A File block downloading method and device 华为技术有限公司 2022-04-19 — — CN disclosed
CN-111131345-B Distributed node finder in multi-cloud computing environment 伊姆西IP控股有限责任公司 2022-04-15 — — CN disclosed
US-20220107929-A1 System and Method Implementing a Distributed Audit Trail THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-04-07 — — US disclosed
US-11296935-B2 Service provision to IoT devices INTEL CORPORATION (US) 2022-04-05 — — US disclosed
US-20220058549-A1 SYSTEMS AND METHODS FOR DISTRIBUTED RESOURCE ALLOCATION CUTTS SHAUN (US) 2022-02-24 — — US disclosed
WO-2022028665-A1 DISTRIBUTED TRAINING IN COMMUNICATION NETWORKS NOKIA TECHNOLOGIES OY (FI) 2022-02-10 — — WO disclosed
US-11233642-B2 Regulating document access HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12575811-B2 Diagnosis of respiratory diseases by capturing aerosolized biomaterial particles using packed bed systems and methods PIEZO1, STUB1, MUC1 TDP1 3886/4885MAPT 3251/4885CES1 4325/4885
US-12585437-B2 System and method for a machine learning source code generation via a holochain network HPN, TSN, SAMM50 TDP1 1572/4885MAPT 2740/4885CES1 2271/4885
US-20260100846-A1 VALIDATING RESULT SETS USING A ZERO TRUST MECHANISM SET, TANK, TES TDP1 941/4885MAPT 2827/4885CES1 3377/4885
US-20260089092-A1 METHOD AND APPARATUS OF ADDRESS RESOLUTION IN A MANHATTAN GRID NETWORK MPHOSPH6, FSCN1, GET3 TDP1 337/4885MAPT 1818/4885CES1 3532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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