Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | CES2 | O00748 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 5/20 | 1.00 |
| ▸ | EPAS1 | Q99814 | 5/20 | 1.00 |
| ▸ | CES1 | P23141 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | IDO1 | P14902 | 4/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 3/20 | 1.00 |
| ▸ | PTPN11 | Q06124 | 3/20 | 1.00 |
| ▸ | ACHE | P22303 | 3/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cryptotanshinone SCHEMBL5940386 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1CES2TDP1 | |
| Cryptotanshinone SCHEMBL29387944 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1CES2TDP1 | |
| Cryptotanshinone SCHEMBL28181278 | 0.91 | MEN1 (0.83) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL29405831 | 0.91 | MEN1 (0.83) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL25752309 | 0.86 | MEN1 (0.75) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL13883845 | 0.85 | MEN1 (0.74) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL3332927 | 0.81 | PTPN1 (0.69) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL22875593 | 0.81 | PTPN1 (0.69) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL31426472 | 0.79 | MEN1 (0.65) | MEN1KMT2AALDH1A1CES2TDP1 | |
| SCHEMBL13855041 | 0.78 | PTPN1 (0.64) | MEN1KMT2AALDH1A1CES2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | EMORY UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | EMORY UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | UNIVERSITY OF ROCHESTER | 2023-07-06 | — | — | US | disclosed |
| US-20230190961-A1 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS | UNIVERSITY OF ROCHESTER | 2023-06-22 | — | — | US | disclosed |
| US-20230190961-A1 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS | UNIVERSITY OF ROCHESTER | 2023-06-22 | — | — | US | disclosed |
| US-20230133695-A1 | METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS | UNIVERSITY OF ROCHESTER | 2023-05-04 | — | — | US | disclosed |
| US-20230133695-A1 | METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS | UNIVERSITY OF ROCHESTER | 2023-05-04 | — | — | US | disclosed |
| US-11207370-B2 | Peptidomimetics for the treatment of coronavirus and picornavirus infections | EMORY UNIVERSITY (US) | 2021-12-28 | — | — | US | disclosed |
| WO-2021231778-A1 | CORONAVIRUS PROTEASE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| US-20210008150-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS | EMORY UNIVERSITY | 2021-01-14 | — | — | US | disclosed |
| US-8513227-B2 | Inhibition of inflammatory cytokine production with tanshinones | THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (US) | 2013-08-20 | — | — | US | disclosed |
| EP-1981489-B1 | INHIBITION OF INFLAMMATORY CYTOKINE PRODUCTION WITH TANSHINONES | THE FEINSTEIN INST MEDICAL RES (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012085222-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USE | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2012-06-28 | — | — | WO | disclosed |
| US-20110257184-A1 | SHP-2 PHOSPHATASE INHIBITOR | CASE WESTERN RESERVE UNIVERSITY | 2011-10-20 | — | — | US | disclosed |
| US-20110257184-A1 | SHP-2 PHOSPHATASE INHIBITOR | CASE WESTERN RESERVE UNIVERSITY | 2011-10-20 | — | — | US | disclosed |
| CN-101862339-A | Use of cryptotanshinone as radiation sensitizing medicament in oncotherapy | INST RADIATION MEDICINE CHINESE ACADEMY MEDICAL SCIENCES | 2010-10-20 | — | — | CN | disclosed |
| WO-2010056041-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING AND PREVENTING HEART DISEASES CAUSED BY ISCHEMIA OR ISCHEMIC REPERFUSION | 주식회사 머젠스 (KR) | 2010-05-20 | — | — | WO | disclosed |
| US-20090221542-A1 | Inhibition of Inflammatory Cytokine Production With Tanshinones | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2009-09-03 | — | — | US | disclosed |
| US-20090221542-A1 | Inhibition of Inflammatory Cytokine Production With Tanshinones | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2009-09-03 | — | — | US | disclosed |
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | SAVIPU PHARMACEUTICALS (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207989-A1 | DITERPENE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR, CANCER AND INFLAMMATORY DISEASES | NFKBIA, EDNRA, EDNRB | MEN1 3639/4885KMT2A 4424/4885ALDH1A1 2108/4885 |
| US-20230133695-A1 | METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS | IKZF3, IKZF1, CXXC4 | MEN1 3156/4885KMT2A 1107/4885ALDH1A1 3617/4885 |
| US-20230190961-A1 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS | TEAD2, MYT1, TEAD1 | MEN1 1045/4885KMT2A 72/4885ALDH1A1 3276/4885 |
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | MYT1, STAT3, MYC | MEN1 2412/4885KMT2A 901/4885ALDH1A1 3434/4885 |
| US-20210008150-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS | ACE2, SARS1, VIP | MEN1 1932/4885KMT2A 2906/4885ALDH1A1 4131/4885 |
| US-20240238323-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES | MTAP, PNP, SARS1 | MEN1 3639/4885KMT2A 779/4885ALDH1A1 1929/4885 |
| US-11207370-B2 | Peptidomimetics for the treatment of coronavirus and picornavirus infections | ACE2, SARS1, VIP | MEN1 1932/4885KMT2A 2906/4885ALDH1A1 4131/4885 |
| US-20110257184-A1 | SHP-2 PHOSPHATASE INHIBITOR | PTPN2, PTPRJ, SHPRH | MEN1 3073/4885KMT2A 1528/4885ALDH1A1 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.