Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106118 | 0.78 | PDE1B (0.36) | HTTNPSR1LMNAPRNPHPGD | |
| SCHEMBL534655 | 0.77 | HTT (0.40) | ESR1ESR2HTTNPSR1LMNA | |
| SCHEMBL533275 | 0.77 | PRNP (0.42) | ESR1ESR2HTTNPSR1LMNA | |
| SCHEMBL23735860 | 0.75 | ESR1 (0.35) | ESR1ESR2HTTLMNAPTPN1 | |
| SCHEMBL534734 | 0.74 | PLAU (0.39) | ESR1ESR2HTTNPSR1LMNA | |
| SCHEMBL1926191 | 0.74 | DYRK1A (0.33) | HTTNPSR1LMNAPRNPHPGD | |
| SCHEMBL1927586 | 0.74 | ESR1 (0.33) | ESR1ESR2HTTNPSR1LMNA | |
| SCHEMBL25702612 | 0.71 | HSP90AA1 (0.54) | HTTMAPTSMN1; SMN2L3MBTL1PKM | |
| SCHEMBL9949429 | 0.71 | MAPT (0.38) | ESR2HTTNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL21403775 | 0.68 | HTT (0.41) | HTTNPSR1LMNAPRNPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185520-B1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| CN-101796030-B | Fungicidal 2-Alkylthio-2-quinolinyloxy-acetamide derivatives | SYNGENTA PARTICIPATIONS AG | 2012-08-22 | — | — | CN | disclosed |
| US-20100256183-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| CN-101796030-A | Fungicidal 2-Alkylthio-2-quinolinyloxy-acetamide derivatives | SYNGENTA PARTICIPATIONS AG | 2010-08-04 | — | — | CN | disclosed |
| EP-2185520-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | Sygenta Participations AG. (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030469-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERITVATIVES | SYGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256183-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | CYP1A2, AADAC, CYP51A1 | ESR1 4305/4885ESR2 3431/4885HTT 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.