Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533275 | 0.81 | PRNP (0.42) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL31716007 | 0.81 | CCR1 (0.42) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL534734 | 0.78 | PLAU (0.39) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL3103568 | 0.78 | CYP3A4 (0.43) | HTTCYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL1927191 | 0.78 | DYRK1A (0.40) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL1927586 | 0.78 | ESR1 (0.33) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL534618 | 0.78 | CYP3A4 (0.34) | HTTCYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL1926191 | 0.78 | DYRK1A (0.33) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL3100730 | 0.77 | ESR1 (0.33) | HTTNPSR1PRNPLMNAHPGD | |
| SCHEMBL21403775 | 0.76 | HTT (0.41) | HTTNPSR1PRNPLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440595-B2 | Fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-14 | — | — | US | disclosed |
| CN-101827817-B | Saturated and insaturated bi- or tricyclic aryloxyacetamide derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC | 2013-05-08 | — | — | CN | disclosed |
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-18 | — | — | US | disclosed |
| EP-2185520-B1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| CN-101796030-B | Fungicidal 2-Alkylthio-2-quinolinyloxy-acetamide derivatives | SYNGENTA PARTICIPATIONS AG | 2012-08-22 | — | — | CN | disclosed |
| EP-2185518-B1 | Aryloxyacetamide derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| EP-2397467-A1 | Quinoline derivatives as fungicides | Syngenta Participations AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2011154240-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-15 | — | — | WO | disclosed |
| EP-2185519-B1 | NOVEL FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-10 | — | — | EP | disclosed |
| EP-2139324-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | Syngeta Participations AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| EP-1817309-B1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009049716-A2 | NOVEL FUNGICIDES | SYGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009030469-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERITVATIVES | SYGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030467-A2 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-17 | — | — | US | disclosed |
| CN-101115748-A | Acetamide compounds as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-30 | — | — | CN | disclosed |
| EP-1817309-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | Syngeta Participations AG (CH) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058700-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096156-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | HTT 3579/4885NPSR1 2913/4885PRNP 3449/4885 |
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | NAT1, DPM1, AADAC | HTT 4197/4885NPSR1 3683/4885PRNP 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.