Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286652 | 0.89 | TSHR (0.63) | ALDH1A1TP53TSHRBCL2L1BAD | |
| SCHEMBL27500596 | 0.87 | TSHR (0.60) | ALDH1A1TP53TSHRBCL2L1BAD | |
| Ammonia Solution, Strong SCHEMBL28659890 | 0.87 | TSHR (0.60) | ALDH1A1TP53TSHRBCL2L1BAD | |
| Butane SCHEMBL27396437 | 0.85 | LMNA (0.62) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| Ethylene SCHEMBL5009683 | 0.85 | TSHR (0.57) | ALDH1A1TP53TSHRBCL2L1BAD | |
| Terephthalic Acid SCHEMBL1482407 | 0.84 | TSHR (0.71) | ALDH1A1TP53TSHRRXRARXRB | |
| Butane SCHEMBL29234656 | 0.84 | TDP1 (0.53) | ALDH1A1MAPTCA1CA2SMN1; SMN2 | |
| SCHEMBL29139554 | 0.83 | BCL2L1 (0.68) | TP53TSHRRXRARXRBBCL2L1 | |
| Benzoic Acid SCHEMBL9105944 | 0.80 | TSHR (0.67) | ALDH1A1MAPTTP53TSHRBCL2L1 | |
| Terephthalic Acid SCHEMBL30899317 | 0.79 | TSHR (0.71) | ALDH1A1TP53TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799913-B2 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | CORTEX PHARMACEUTICALS, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| EP-1448537-A4 | CARBONYLBENZOXAZINE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMA INC (US) | 2005-05-04 | — | — | EP | disclosed |
| US-20040259871-A1 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | CORTEX PHARMACEUTICALS, INC | 2004-12-23 | — | — | US | disclosed |
| EP-1448537-A2 | CARBONYLBENZOXAZINE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045315-A2 | CARBONYLBENZOXAZINE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259871-A1 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | GAP43, GRIN2B, GRIN2A | ALDH1A1 2536/4885MAPT 626/4885TP53 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.