SCHEMBL29139554

SCHEMBL29139554

O=C(O)c1ccc(-c2ccc(C(=O)OO)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.68
BAD Q92934 1/20 0.68
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
HSD17B10 Q99714 2/20 0.52
RXRA P19793 4/20 0.50
RXRB P28702 3/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
TTR P02766 1/20 0.48
SRD5A2 P31213 2/20 0.48
EGFR P00533 1/20 0.47
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46
DRD1 P21728 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1286652 0.93 TSHR (0.63) BCL2L1BADTP53TSHRCA12
Ammonia Solution, Strong SCHEMBL28659890 0.91 TSHR (0.60) BCL2L1BADTP53TSHRCA12
SCHEMBL27500596 0.91 TSHR (0.60) BCL2L1BADTP53TSHRCA12
SCHEMBL3876168 0.91 BCL2L1 (0.52) BCL2L1BADKDM4ELMNACA12
Ethylene SCHEMBL5009683 0.88 TSHR (0.57) BCL2L1BADTP53TSHRCA12
SCHEMBL8722051 0.86 PDCD1 (0.60) BCL2L1BADKDM4ELMNAEGFR
SCHEMBL18267477 0.86 RXRA (0.61) BCL2L1BADHSD17B10RXRARXRB
SCHEMBL2807622 0.84 BCL2L1 (0.58) BCL2L1BADTP53TSHRHSD17B10
Benzoic Acid SCHEMBL9105944 0.84 TSHR (0.67) BCL2L1BADTP53TSHRHSD17B10
SCHEMBL17090378 0.83 ALDH1A1 (0.59) BCL2L1BADRXRARXRBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111132755-B Overcoming two carbon dioxide adsorption steps in diamine-attached metal-organic frameworks 加利福尼亚大学董事会 2023-12-19 CN disclosed