Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.32 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | USP19 | O94966 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 5/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | BMX | P51813 | 2/20 | 0.31 |
| ▸ | ITK | Q08881 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333555 | 1.00 | CCNC (0.35) | CCNCCDK8MAPK1SCD5PIK3CA | |
| SCHEMBL29333783 | 0.86 | MAPK1 (0.34) | CCNCCDK8MAPK1PIK3CABTK | |
| SCHEMBL31008618 | 0.86 | MAPK1 (0.34) | CCNCCDK8MAPK1PIK3CABTK | |
| SCHEMBL31008658 | 0.86 | PIK3CA (0.39) | CCNCCDK8MAPK1PIK3CAMTOR | |
| SCHEMBL31008588 | 0.86 | JAK2 (0.35) | CCNCCDK8MAPK1USP19BTK | |
| SCHEMBL29333491 | 0.86 | JAK2 (0.35) | CCNCCDK8MAPK1USP19BTK | |
| SCHEMBL29333753 | 0.86 | PIK3CA (0.39) | CCNCCDK8MAPK1PIK3CAMTOR | |
| SCHEMBL31008544 | 0.85 | MAPK1 (0.35) | CCNCCDK8MAPK1PIK3CABTK | |
| SCHEMBL29333751 | 0.85 | MAPK1 (0.35) | CCNCCDK8MAPK1PIK3CABTK | |
| SCHEMBL31008538 | 0.85 | MAPK1 (0.34) | CCNCCDK8MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226114-A1 | INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226114-A1 | INHIBITORS AND USES THEREOF | KEAP1, NQO1, NFE2L2 | CCNC 4349/4885CDK8 1776/4885MAPK1 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.