⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028069 | 0.72 | — | — | |
| SCHEMBL1278746 | 0.63 | — | — | |
| SCHEMBL434049 | 0.62 | — | — | |
| Tetrahydrothiophene SCHEMBL8721515 | 0.60 | GLS (0.37) | — | |
| SCHEMBL15686686 | 0.59 | MEN1 (0.42) | — | |
| SCHEMBL17790297 | 0.58 | — | — | |
| SCHEMBL8404556 | 0.58 | — | — | |
| SCHEMBL5997198 | 0.58 | — | — | |
| SCHEMBL174459 | 0.58 | — | — | |
| SCHEMBL309305 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646410-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB Science (FR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024146923-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB SCIENCE (FR) | 2024-07-11 | — | — | WO | disclosed |