Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KAT7 | O95251 | 13/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 13/20 | 0.42 |
| ▸ | KAT6B | Q8WYB5 | 9/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 9/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31010070 | 0.84 | KAT7 (0.35) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31010071 | 0.80 | KAT7 (0.50) | HTTKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL28205957 | 0.78 | CYP11B1 (0.49) | HTTKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL30538376 | 0.77 | GAA (0.51) | HTTKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL21668143 | 0.74 | MEN1 (0.42) | HTTKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL19366156 | 0.74 | HTT (0.40) | HTTKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL3319825 | 0.73 | MAPT (0.55) | HTTKAT7KAT6AGAAMAPT | |
| SCHEMBL5905949 | 0.73 | NOS3 (0.50) | HTTGAAMAPTMEN1TSHR | |
| SCHEMBL30046633 | 0.73 | MEN1 (0.59) | HTTKAT7KAT6AGAAMAPT | |
| SCHEMBL5792386 | 0.73 | MEN1 (0.59) | HTTKAT7KAT6AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646410-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB Science (FR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024146923-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB SCIENCE (FR) | 2024-07-11 | — | — | WO | disclosed |