SCHEMBL31010070

SCHEMBL31010070

[2H]c1cnn(Cc2cc(C)c(OC)c(C)c2)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 17/20 0.35
KAT6A Q92794 17/20 0.35
KAT6B Q8WYB5 13/20 0.34
KAT8 Q9H7Z6 13/20 0.34
KAT5 Q92993 12/20 0.34
DHFR P00374 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31010043 0.84 HTT (0.42) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL31010200 0.68 CYP19A1 (0.52)
SCHEMBL8377139 0.66 PTGS2 (0.60) DHFR
SCHEMBL16201822 0.66 C5AR1 (0.41) DHFR
SCHEMBL31010071 0.65 KAT7 (0.50) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL5828450 0.65 DHFR (0.41) DHFR
SCHEMBL13304653 0.64 DHFR (0.51) DHFR
SCHEMBL29746497 0.63
SCHEMBL29918844 0.62
SCHEMBL18028307 0.62 HSP90AA1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646410-A1 TUBULIN POLYMERIZATION INHIBITORS AB Science (FR) 2025-11-12 EP disclosed
WO-2024146923-A1 TUBULIN POLYMERIZATION INHIBITORS AB SCIENCE (FR) 2024-07-11 WO disclosed