Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856632 | 0.83 | LRRK2 (0.55) | LRRK2CYP1A2ALDH1A1LMNACOMT | |
| SCHEMBL25378342 | 0.77 | ALDH1A1 (0.48) | LRRK2CYP1A2ALDH1A1LMNACOMT | |
| SCHEMBL17630846 | 0.76 | LRRK2 (0.52) | LRRK2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL29103216 | 0.74 | ALDH1A1 (0.56) | LRRK2CYP1A2ALDH1A1LMNACOMT | |
| SCHEMBL31010151 | 0.74 | ALDH1A1 (0.43) | LRRK2CYP1A2ALDH1A1LMNACOMT | |
| SCHEMBL4562366 | 0.72 | LRRK2 (0.69) | LRRK2CYP1A2CSF1RMKNK2 | |
| SCHEMBL4561033 | 0.72 | LRRK2 (0.69) | LRRK2CYP1A2ALDH1A1LMNA | |
| SCHEMBL5021245 | 0.72 | LRRK2 (0.69) | LRRK2CYP1A2ALDH1A1LMNA | |
| SCHEMBL4539554 | 0.71 | LRRK2 (0.53) | LRRK2CYP1A2ALDH1A1LMNA | |
| SCHEMBL9969926 | 0.70 | LRRK2 (1.00) | LRRK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646410-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB Science (FR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024146923-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB SCIENCE (FR) | 2024-07-11 | — | — | WO | disclosed |