Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.53 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 7/20 | 0.52 |
| ▸ | HTR7 | P34969 | 7/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447341 | 0.98 | KCNH2 (0.59) | LTA4HKCNH2LMNAPKMTSHR | |
| SCHEMBL13940688 | 0.87 | NPC1 (0.60) | LTA4HKCNH2LMNAPKMTSHR | |
| SCHEMBL1515069 | 0.84 | KCNH2 (0.55) | KCNH2LMNAPKMTSHRSMN1; SMN2 | |
| SCHEMBL24691383 | 0.83 | DRD2 (0.59) | LTA4HKCNH2UBE2TASIC3HTR1A | |
| SCHEMBL23336158 | 0.81 | SMN1; SMN2 (0.57) | KCNH2LMNAPKMTSHRSMN1; SMN2 | |
| SCHEMBL24986914 | 0.78 | L3MBTL1 (0.53) | KCNH2LMNAPKMTSHRSMN1; SMN2 | |
| SCHEMBL14761335 | 0.78 | DRD4 (0.52) | KCNH2LMNAPKMTSHRSMN1; SMN2 | |
| SCHEMBL24983962 | 0.78 | L3MBTL1 (0.56) | KCNH2LMNAPKMTSHRSMN1; SMN2 | |
| SCHEMBL10562250 | 0.78 | DRD3 (0.58) | KCNH2LMNAPKMTSHRSMN1; SMN2 | |
| SCHEMBL16837184 | 0.77 | NPC1 (0.52) | KCNH2LMNAPKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | NOVARTIS AG (CH) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | IKZF1, IKZF2, IKZF3 | LTA4H 4650/4885KCNH2 3008/4885LMNA 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.