Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091419 | 0.92 | OPRM1 (0.53) | OPRM1HTR1ASLC6A4OPRD1OPRK1 | |
| SCHEMBL3091628 | 0.89 | OPRM1 (0.75) | OPRM1 | |
| SCHEMBL3094944 | 0.88 | OPRM1 (0.68) | OPRM1OPRD1OPRK1ACHESLC22A1 | |
| Hydrochloric Acid SCHEMBL3089658 | 0.87 | OPRM1 (0.67) | OPRM1OPRD1OPRK1ACHESLC22A1 | |
| SCHEMBL3091587 | 0.86 | OPRM1 (0.63) | OPRM1OPRD1OPRK1ACHESLC22A1 | |
| SCHEMBL4545439 | 0.84 | OPRM1 (0.81) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL3089648 | 0.82 | OPRM1 (0.63) | OPRM1OPRD1OPRK1ACHESLC22A1 | |
| SCHEMBL3091530 | 0.81 | OPRM1 (0.59) | OPRM1OPRD1OPRK1ACHESLC22A1 | |
| SCHEMBL3083010 | 0.81 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SLC22A1NR1I2 | |
| SCHEMBL3083237 | 0.81 | OPRM1 (0.59) | OPRM1OPRD1OPRK1ACHESLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | claimed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | claimed |
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | disclosed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | disclosed |
| EP-1987001-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NeuroSearch A/S (DK) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093603-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | OPRL1, OPRM1, OPRK1 | OPRM1 2/4885HTR1A 33/4885SLC6A4 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.