SCHEMBL31011031

SCHEMBL31011031

Cc1cc(-n2nc3c(c2NC(=O)NN)[C@H](C)N(C(=O)OC(C)(C)C)CC3)cc(C)c1F

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 1/20 0.34
▸ C5AR1 P21730 4/20 0.33
▸ NTRK1 P04629 3/20 0.32
▸ LMNA P02545 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ TP53 P04637 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ HPGDS O60760 1/20 0.31
▸ GLP1R P43220 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31011044 1.00 THRB (0.34) THRBC5AR1NTRK1LMNANPSR1
SCHEMBL31472049 0.87 C5AR1 (0.33) THRBC5AR1NTRK1LMNANPSR1
SCHEMBL28952289 0.86 NTRK1 (0.34) THRBC5AR1NTRK1GLP1R
SCHEMBL21183622 0.86 THRB (0.31) THRBNTRK1
SCHEMBL20014817 0.86 NTRK1 (0.34) THRBC5AR1NTRK1GLP1R
SCHEMBL31424283 0.85 THRB (0.32) THRBC5AR1LMNANPSR1
SCHEMBL20014821 0.85 NR1H2 (0.33) THRBC5AR1LMNANPSR1TP53
SCHEMBL28952435 0.85 NR1H2 (0.33) THRBC5AR1LMNANPSR1TP53
SCHEMBL22909652 0.84 THRB (0.30) THRB
SCHEMBL31692337 0.83 THRB (0.33) THRBC5AR1LMNANPSR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652167-A1 GLP-1R AGONISTS AND USES THEREOF Fochon Biosciences, Ltd. (CN) 2025-11-26 — — EP disclosed
WO-2024153070-A1 GLP-1R AGONISTS AND USES THEREOF FOCHON BIOSCIENCES, LTD. (CN) 2024-07-25 — — WO disclosed
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