SCHEMBL31013294

SCHEMBL31013294

CC(=O)OC1CCN(c2ncc(C(F)(F)F)cc2N)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.55
KMT2A Q03164 4/20 0.55
CYP2C9 P11712 3/20 0.55
CYP2C19 P33261 3/20 0.55
KDM4E B2RXH2 3/20 0.55
MEN1 O00255 3/20 0.55
GAA P10253 1/20 0.55
SMN1; SMN2 Q16637 8/20 0.54
ALDH1A1 P00352 5/20 0.53
HPGD P15428 2/20 0.53
LMNA P02545 2/20 0.49
ACACB O00763 1/20 0.46
POLB P06746 1/20 0.46
HTT P42858 1/20 0.46
HRH3 Q9Y5N1 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
RECQL P46063 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31013279 0.84 MAPT (0.52) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL31013260 0.84 MDM2 (0.42) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL31013278 0.84 MDM2 (0.42) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL28497343 0.78 MAPT (0.71) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL7192215 0.76 KCNQ3 (0.41) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL7192211 0.76 KCNQ3 (0.41) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL31013255 0.76 SCN10A (0.47) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL5252865 0.76 OPRK1 (0.46) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL31013303 0.75 GPR6 (0.55) MAPTKMT2ACYP2C9CYP2C19KDM4E
SCHEMBL31410510 0.74 MEN1 (0.56) MAPTKMT2AMEN1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646263-A1 SPRK1 INHIBITORS AND METHODS OF USE Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) 2025-11-12 EP disclosed
WO-2024155864-A1 SPRK1 INHIBITORS AND METHODS OF USE ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) 2024-07-25 WO disclosed