Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31013274 | 0.85 | CXCR3 (0.49) | SCN10ASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31013258 | 0.82 | SMN1; SMN2 (0.44) | SCN10ASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31013294 | 0.76 | MAPT (0.55) | SCN10ASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31410462 | 0.74 | MEN1 (0.56) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL31410510 | 0.74 | MEN1 (0.56) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL31013268 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1282773 | 0.73 | OPRK1 (0.44) | SCN10A | |
| SCHEMBL3435696 | 0.73 | OPRK1 (0.42) | SCN10ASMN1; SMN2LMNAMAPTCYP2C19 | |
| SCHEMBL31013296 | 0.72 | CXCR3 (0.51) | SCN10ASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL21906068 | 0.71 | SCN10A (0.56) | SCN10AMEN1KMT2ANR1I2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646263-A1 | SPRK1 INHIBITORS AND METHODS OF USE | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024155864-A1 | SPRK1 INHIBITORS AND METHODS OF USE | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |