Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31013274 | 0.88 | CXCR3 (0.49) | CXCR3HTTALDH1A1MAPK1CYP2C9 | |
| SCHEMBL31013298 | 0.87 | CXCR3 (0.53) | CXCR3HTTALDH1A1MAPK1POLB | |
| SCHEMBL29274197 | 0.81 | SMN1; SMN2 (0.48) | CXCR3HTTALDH1A1MAPK1POLB | |
| SCHEMBL31013249 | 0.80 | CXCR3 (0.52) | CXCR3HTTALDH1A1MAPK1POLB | |
| SCHEMBL31013257 | 0.78 | MAPT (0.62) | CXCR3HTTALDH1A1MAPK1POLB | |
| SCHEMBL31013272 | 0.78 | MAPT (0.62) | CXCR3HTTALDH1A1MAPK1POLB | |
| SCHEMBL29274207 | 0.77 | SMN1; SMN2 (0.60) | CXCR3HTTALDH1A1MAPK1POLB | |
| SCHEMBL31013279 | 0.76 | MAPT (0.52) | CXCR3HTTALDH1A1POLBCYP2C9 | |
| SCHEMBL31410495 | 0.76 | MEN1 (0.53) | CXCR3ALDH1A1NR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL29841916 | 0.76 | MEN1 (0.53) | CXCR3ALDH1A1NR1H2NR1H3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646263-A1 | SPRK1 INHIBITORS AND METHODS OF USE | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024155864-A1 | SPRK1 INHIBITORS AND METHODS OF USE | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |