Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29274207 | 0.84 | SMN1; SMN2 (0.60) | CXCR3ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL29274197 | 0.84 | SMN1; SMN2 (0.48) | CXCR3ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL31013298 | 0.83 | CXCR3 (0.53) | CXCR3ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL31013257 | 0.82 | MAPT (0.62) | CXCR3ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL31013272 | 0.82 | MAPT (0.62) | CXCR3ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL1981534 | 0.81 | ALDH1A1 (0.74) | SIRT6ALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL31410495 | 0.81 | MEN1 (0.53) | CXCR3ALDH1A1SMN1; SMN2LMNANR1H2 | |
| SCHEMBL29841916 | 0.81 | MEN1 (0.53) | CXCR3ALDH1A1SMN1; SMN2LMNANR1H2 | |
| SCHEMBL24968952 | 0.80 | SMN1; SMN2 (0.51) | CXCR3ALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL31013296 | 0.80 | CXCR3 (0.51) | CXCR3ALDH1A1MAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646263-A1 | SPRK1 INHIBITORS AND METHODS OF USE | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024155864-A1 | SPRK1 INHIBITORS AND METHODS OF USE | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |