Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31013977 | 0.91 | ESR2 (0.42) | ESR2NR1H2ALDH1A1NPC1MAPK1 | |
| SCHEMBL31013866 | 0.89 | ALDH1A1 (0.43) | ESR2NR1H2ALDH1A1MAPTCCR2 | |
| SCHEMBL30789219 | 0.86 | ESR2 (0.39) | ESR2NR1H2ALDH1A1NPC1MAPK1 | |
| SCHEMBL24913899 | 0.86 | ESR2 (0.39) | ESR2NR1H2L3MBTL1MTORLRRK2 | |
| SCHEMBL29168680 | 0.86 | ESR2 (0.39) | ESR2NR1H2ALDH1A1NPC1MAPK1 | |
| SCHEMBL24914052 | 0.86 | HRH3 (0.41) | ESR2NR1H2ALDH1A1IGF1R | |
| SCHEMBL24913887 | 0.86 | GPR119 (0.38) | ESR2NR1H2ALDH1A1NPC1MAPK1 | |
| SCHEMBL30156900 | 0.86 | GPR119 (0.38) | ESR2NR1H2ALDH1A1NPC1MAPK1 | |
| SCHEMBL24913992 | 0.85 | ESR2 (0.43) | ESR2NR1H2ALDH1A1NPC1MAPK1 | |
| SCHEMBL24913832 | 0.85 | ESR2 (0.43) | ESR2NR1H2ALDH1A1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651955-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153947-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2024-07-25 | — | — | WO | disclosed |