Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.48 |
| ▸ | TRAP1 | Q12931 | 5/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913916 | 0.92 | ESR2 (0.45) | MGLLABHD6TRAP1HSP90B1ESR2 | |
| SCHEMBL30156757 | 0.92 | ESR2 (0.45) | MGLLABHD6TRAP1HSP90B1ESR2 | |
| SCHEMBL31013918 | 0.85 | MGLL (0.45) | MGLLABHD6TRAP1HSP90B1KDM4E | |
| SCHEMBL30550460 | 0.82 | HDAC1 (0.44) | ABHD6ESR2NR1H2KDM4EALDH1A1 | |
| SCHEMBL29069135 | 0.82 | HDAC1 (0.44) | ABHD6ESR2NR1H2KDM4EALDH1A1 | |
| SCHEMBL3100497 | 0.82 | ABHD6 (0.69) | MGLLABHD6TRAP1HSP90B1ESR2 | |
| SCHEMBL30789204 | 0.80 | ESR2 (0.46) | ABHD6ESR2NR1H2GPR119KDM4E | |
| SCHEMBL17463409 | 0.80 | ESR2 (0.46) | ESR2NR1H2GPR119KDM4E | |
| SCHEMBL30156709 | 0.80 | ESR2 (0.46) | ABHD6ESR2NR1H2GPR119KDM4E | |
| SCHEMBL19357854 | 0.78 | HDAC1 (0.42) | ABHD6ESR2NR1H2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| EP-4651955-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024153947-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2024-07-25 | — | — | WO | disclosed |