SCHEMBL31014147

SCHEMBL31014147

COC(=O)c1ccc(C=Cc2ccccc2)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.56
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA12 O43570 1/20 0.54
CA7 P43166 1/20 0.54
XDH P47989 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
P4HB P07237 3/20 0.50
TRPA1 O75762 1/20 0.49
NPC1 O15118 4/20 0.48
RAB9A P51151 4/20 0.48
POLB P06746 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
LMNA P02545 3/20 0.47
HPGD P15428 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31014140 1.00 PTPN1 (0.56) PTPN1CA1CA2CA12CA7
SCHEMBL31014138 0.86 PTPN1 (0.57) PTPN1CA1CA2CA12CA7
SCHEMBL31014139 0.85 PTPN1 (0.52) PTPN1CA1CA2CA12CA7
SCHEMBL7035797 0.84 LMNA (0.56) PTPN1CA1CA2CA12CA7
SCHEMBL7035796 0.84 LMNA (0.56) PTPN1CA1CA2CA12CA7
SCHEMBL31317684 0.82 PTPN1 (0.49) PTPN1CA1CA2CA12CA7
SCHEMBL14594588 0.81 ALDH1A1 (0.49) PTPN1CA1CA2P4HBNPC1
SCHEMBL521422 0.81 TSHR (0.67) PTPN1CA1CA2CA12CA7
SCHEMBL521421 0.81 TSHR (0.67) PTPN1CA1CA2CA12CA7
SCHEMBL11832993 0.81 ALDH1A1 (0.51) PTPN1CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439934-A Adamantane compound containing conjugated vinyl and preparation and application thereof 浙江大学 2024-08-06 CN disclosed